These shows removed the mystical nature of the character, instead depicting Minerva as a geneticist who inadvertently transformed herself into the Cheetah. The Barbara Ann Minerva version played a recurring role on both Justice League and Justice League Unlimited (voiced by Sheryl Lee Ralph). Cheetah: Beyond the ComicsCheetah's first appearance outside the comics came in the animated series Challenge of the Super Friends, with the Priscilla Rich version (voiced by Marlene Aragon) serving as a member of the Legion of Doom. However, in the wake of DC's New 52 reboot, Minerva is now depicted as the only Cheetah, and both Rich and Domaine were merely two of her temporary cover identities. Originally, both Priscilla Rich and Deborah Domaine remained a part of DC continuity, with Minerva killing the former to strengthen her claim to the mantle. Minerva's connection to past Cheetahs has also changed with time. Sebastian Ballesteros became the first man to take up the mantle. Minerva's appearance, motivation and powers have shifted during that time, and she's sometimes been portrayed as more anti-hero than true villain. Minerva has remained in the role ever since, apart from a brief period where she was replaced by Sebastian Ballesteros in 2001's Wonder Woman #170 he was the sole man to take on the mantle to date. Unfortunately, the chemical was only intended to be used on virgins, causing Minerva to experience terrible pain in her human form and an insatiable bloodlust in her cheetah form.

Minerva was depicted as an ambitious archaeologist who ingested a rare chemical brewed by worshipers of Urzkartaga, craving the immortality the chemical would bestow upon her. Len Wein and George Perez introduced the Barbara Ann Minerva version in 1987's Wonder Woman #7, making her the first Cheetah to possess superhuman powers and a connection to the gods.

Following the events of 1985's Crisis on Infinite Earths, DC drastically revamped the Wonder Woman franchise and Cheetah's role therein.

The niece of Rich, Domaine was brainwashed by the terrorist organization Kobra to take up her aunt's mantle and battle Wonder Woman despite their friendship. The Deborah Domaine Cheetah was introduced in 1980's Wonder Woman #274.

Cheetah batman the brave and the bold